Drug Induced QTc Prologation
Drugs to Avoid
Drug-Induced QT Prolongation
Drug induced QT prolongation
Drug Induced QT Prolongation
Q-Tc Interval Prolongation by Drugs: Antiarrhythmic Drug Actions
Center for Education and Research Therapeutics
Publications
1 Methadone, QTc prolongation and torsades de pointes: Current concepts, management and a hidden twist in the tale? Mujtaba S, Romero J, Taub CC.J Cardiovasc Dis Res. 2013 Dec;4(4):229-235. Epub 2013 Nov 16. Review. PMID:24653586[PubMed - as supplied by publisher]Related citations Select item 24438862 2 Racial susceptibility for QT prolongation in acute drug overdoses. Manini AF, Stimmel B, Vlahov D.J Electrocardiol. 2014 Mar-Apr;47(2):244-50. doi: 10.1016/j.jelectrocard.2013.12.002. Epub 2013 Dec 4. PMID:24438862[PubMed - in process]Related citations Select item 24399590 3 Giant drug-induced QT prolongation > 800 ms with alternans of terminal portion of T wave and J wave in a normothermic patient. Kukla P, Baranchuk A, Jastrzębski M, Bryniarski L, Baranowski R.Kardiol Pol. 2013;71(12):1306-7. doi: 10.5603/KP.2013.0330. PMID:24399590[PubMed - indexed for MEDLINE] Free ArticleRelated citations Select item 24388488 4 Drug-induced QT prolongation when QT interval is measured in each of the 12 ECG leads in men and women in a thorough QT study. Panicker GK, Salvi V, Karnad DR, Chakraborty S, Manohar D, Lokhandwala Y, Kothari S.J Electrocardiol. 2014 Mar-Apr;47(2):155-7. doi: 10.1016/j.jelectrocard.2013.11.004. Epub 2013 Nov 27. PMID:24388488[PubMed - in process]Related citations Select item 24372552 5 Detection of QTc interval prolongation using jacket telemetry in conscious non-human primates: comparison with implanted telemetry. Derakhchan K, Chui RW, Stevens D, Gu W, Vargas HM.Br J Pharmacol. 2014 Jan;171(2):509-22. doi: 10.1111/bph.12484. PMID:24372552[PubMed - in process]Related citations Select item 24353019 6 Prolonged QT interval by methadone: relevance for daily practice? A prospective study in patients with cancer and noncancer pain. van den Beuken-van Everdingen MH, Geurts JW, Patijn J.J Opioid Manag. 2013 Jul-Aug;9(4):263-7. doi: 10.5055/jom.2013.0167. PMID:24353019[PubMed - indexed for MEDLINE]Related citations Select item 24327451 7 Evidence for a crucial modulating role of the sodium channel in the QTc prolongation related to antipsychotics. Silvestre JS, O'Neill MF, Prous JR.J Psychopharmacol. 2014 Apr;28(4):329-40. doi: 10.1177/0269881113515064. Epub 2013 Dec 10. PMID:24327451[PubMed - in process]Related citations Select item 24314265 8 Safety and efficacy of vemurafenib in end stage renal failure. Iddawela M, Crook S, George L, Lakkaraju A, Nanayakkara N, Hunt R, Adam WR.BMC Cancer. 2013 Dec 6;13:581. doi: 10.1186/1471-2407-13-581. PMID:24314265[PubMed - indexed for MEDLINE] Free ArticleRelated citations Select item 24313745 9 Adverse effects associated with high-dose olanzapine therapy in patients admitted to inpatient psychiatric care. Petersen AB, Andersen SE, Christensen M, Larsen HL.Clin Toxicol (Phila). 2014 Jan;52(1):39-43. doi: 10.3109/15563650.2013.862258. Epub 2013 Dec 9. PMID:24313745[PubMed - indexed for MEDLINE]Related citations Select item 24305646 10 Impact of anaesthetic drugs and adjuvants on ECG markers of torsadogenicity. Staikou C, Stamelos M, Stavroulakis E.Br J Anaesth. 2014 Feb;112(2):217-30. doi: 10.1093/bja/aet412. Epub 2013 Dec 3. Review. PMID:24305646[PubMed - indexed for MEDLINE]Related citations Select item 24301687 11 Assessment of drug-induced torsade de pointes risk for hospitalized high-risk patients receiving QT-prolonging agents. Jardin CG, Putney D, Michaud S.Ann Pharmacother. 2014 Feb;48(2):196-202. doi: 10.1177/1060028013512614. Epub 2013 Dec 3. PMID:24301687[PubMed - in process]Related citations Select item 24256556 12 Ibandronate and ventricular arrhythmia risk. Bonilla IM, Vargas-Pinto P, Nishijima Y, Pedraza-Toscano A, Ho HT, Long VP 3rd, Belevych AE, Glynn P, Houmsse M, Rhodes T, Weiss R, Hund TJ, Hamlin RL, Györke S, Carnes CA.J Cardiovasc Electrophysiol. 2014 Mar;25(3):299-306. doi: 10.1111/jce.12327. Epub 2013 Dec 20. PMID:24256556[PubMed - in process]Related citations Select item 24252288 13 QTc compared to JTc for monitoring drug-induced repolarization changes in the setting of ventricular pacing. Tsai SF, Houmsse M, Dakhil B, Augostini R, Hummel JD, Kalbfleisch SJ, Liu Z, Love C, Rhodes T, Tyler J, Weiss R, Hamam I, Winner M, Daoud EG.Heart Rhythm. 2014 Mar;11(3):485-91. doi: 10.1016/j.hrthm.2013.11.017. Epub 2013 Nov 16. PMID:24252288[PubMed - in process]Related citations Select item 24249315 14 Quetiapine versus other atypical antipsychotics for schizophrenia. Asmal L, Flegar SJ, Wang J, Rummel-Kluge C, Komossa K, Leucht S.Cochrane Database Syst Rev. 2013 Nov 18;11:CD006625. doi: 10.1002/14651858.CD006625.pub3. PMID:24249315[PubMed - in process]Related citations Select item 24211841 15 ECG parameters in children and adolescents treated with aripiprazole and risperidone. Germanò E, Italiano D, Lamberti M, Guerriero L, Privitera C, D'Amico G, Siracusano R, Ingrassia M, Spina E, Calabrò MP, Gagliano A.Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jun 3;51:23-7. doi: 10.1016/j.pnpbp.2013.10.020. Epub 2013 Nov 5. PMID:24211841[PubMed - in process]Related citations Select item 24211675 16 Effects of probucol, a typical hERG expression inhibitor, on in vivo QT interval prolongation in conscious dogs. Nogawa H, Kawai T, Yajima M, Miura M, Ogawa T, Murakami K.Eur J Pharmacol. 2013 Nov 15;720(1-3):29-37. doi: 10.1016/j.ejphar.2013.10.056. Epub 2013 Nov 5. PMID:24211675[PubMed - in process]Related citations Select item 24167694 17 Methadone, QTc interval prolongation and torsade de pointes: Case reports offer the best understanding of this problem. Vieweg WV, Hasnain M, Howland RH, Clausen T, Koneru JN, Kogut C, Crouse EL, Hancox JC, Fernandez A, Pandurangi AK.Ther Adv Psychopharmacol. 2013 Aug;3(4):219-32. doi: 10.1177/2045125312469982. PMID:24167694[PubMed] Free PMC ArticleRelated citations Select item 24135462 18 Serum concentration of eperisone hydrochloride correlates with QT interval. Yamagiwa T, Morita S, Amino M, Miura N, Saito T, Inokuchi S.Am J Emerg Med. 2014 Jan;32(1):75-7. doi: 10.1016/j.ajem.2013.09.006. Epub 2013 Oct 15. PMID:24135462[PubMed - indexed for MEDLINE]Related citations Select item 24131328 19 Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. Al-Abri SA, Orengo JP, Hayashi S, Thoren KL, Benowitz NL, Olson KR.Clin Toxicol (Phila). 2013 Dec;51(10):1230-4. doi: 10.3109/15563650.2013.849349. Epub 2013 Oct 17. PMID:24131328[PubMed - indexed for MEDLINE]Related citations Select item 24120715 20 High-quality triplicate electrocardiogram monitoring in a first-in-man study: potential for early detection of drug-induced QT prolongation. He YL, Zhang Y, Yan JH, Zhou W, Komjathy S, Taylor A.Int J Clin Pharmacol Ther. 2013 Dec;51(12):948-57. doi: 10.5414/CP201949. PMID:24120715[PubMed - indexed for MEDLINE]Related citations
21
Compound ICA-105574 prevents arrhythmias induced by cardiac delayed repolarization. Meng J, Shi C, Li L, Du Y, Xu Y. Eur J Pharmacol. 2013 Oct 15;718(1-3):87-97. doi: 10.1016/j.ejphar.2013.09.011. Epub 2013 Sep 13. Related citations Select item 24020938
22 QT interval prolongation and the risk of torsades de pointes: essentials for clinicians. Trinkley KE, Lee Page R 2nd, Lien H, Yamanouye K, Tisdale JE. Curr Med Res Opin. 2013 Dec;29(12):1719-26. doi: 10.1185/03007995.2013.840568. Epub 2013 Sep 23. Related citations Select item 23999693 23 Exposure-response analysis of pertuzumab in HER2-positive metastatic breast cancer: absence of effect on QTc prolongation and other ECG parameters. Garg A, Li J, Clark E, Knott A, Carrothers TJ, Marier JF, Cortés J, Brewster M, Visich J, Lum B. Cancer Chemother Pharmacol. 2013 Nov;72(5):1133-41. doi: 10.1007/s00280-013-2279-6. Epub 2013 Sep 3. Free PMC Article Related citations Select item 23995305 24 Slow delayed rectifier potassium current blockade contributes importantly to drug-induced long QT syndrome. Veerman CC, Verkerk AO, Blom MT, Klemens CA, Langendijk PN, van Ginneken AC, Wilders R, Tan HL. Circ Arrhythm Electrophysiol. 2013 Oct;6(5):1002-9. doi: 10.1161/CIRCEP.113.000239. Epub 2013 Aug 31. Related citations Select item 23920817 25 Early detection of QT interval prolongation from the ECG database system. Yamaguchi I, Fujita H, Ohe K. Stud Health Technol Inform. 2013;192:1043. Related citations Select item 23899678 26 Risk of QTc prolongation in a cohort of opioid-dependent HIV-infected patients on methadone maintenance therapy. Vallecillo G, Mojal S, Roquer A, Martinez D, Rossi P, Fonseca F, Muga R, Torrens M. Clin Infect Dis. 2013 Oct;57(8):1189-94. doi: 10.1093/cid/cit467. Epub 2013 Jul 29. Related citations Select item 23892340 27 Spatial correlation of action potential duration and diastolic dysfunction in transgenic and drug-induced LQT2 rabbits. Odening KE, Jung BA, Lang CN, Cabrera Lozoya R, Ziupa D, Menza M, Relan J, Franke G, Perez Feliz S, Koren G, Zehender M, Bode C, Brunner M, Sermesant M, Föll D. Heart Rhythm. 2013 Oct;10(10):1533-41. doi: 10.1016/j.hrthm.2013.07.038. Epub 2013 Jul 26. Related citations Select item 23869656 28 A case series of patients with lamotrigine toxicity at one center from 2003 to 2012. Moore PW, Donovan JW, Burkhart KK, Haggerty D. Clin Toxicol (Phila). 2013 Aug;51(7):545-9. doi: 10.3109/15563650.2013.818685. Epub 2013 Jul 19. Related citations Select item 23842012 29 Termination of clozapine treatment due to medical reasons: when is it warranted and how can it be avoided? Nielsen J, Correll CU, Manu P, Kane JM. J Clin Psychiatry. 2013 Jun;74(6):603-13; quiz 613. doi: 10.4088/JCP.12r08064. Review. Related citations Select item 23833046 30 Epidemiology of symptomatic drug-induced long QT syndrome and Torsade de Pointes in Germany. Sarganas G, Garbe E, Klimpel A, Hering RC, Bronder E, Haverkamp W. Europace. 2014 Jan;16(1):101-8. doi: 10.1093/europace/eut214. Epub 2013 Jul 5. Related citations Select item 23820570 31 QTc interval screening in an opioid treatment program. Katz DF, Sun J, Khatri V, Kao D, Bucher-Bartelson B, Traut C, Lundin-Martinez J, Goodman M, Mehler PS, Krantz MJ. Am J Cardiol. 2013 Oct 1;112(7):1013-8. doi: 10.1016/j.amjcard.2013.05.037. Epub 2013 Jun 29. PMID: 23820570 [PubMed - indexed for MEDLINE] Related citations Select item 23819796 32 Are women more susceptible than men to drug-induced QT prolongation? Concentration-QTcmodelling in a phase 1 study with oral rac-sotalol. Darpo B, Karnad DR, Badilini F, Florian J, Garnett CE, Kothari S, Panicker GK, Sarapa N. Br J Clin Pharmacol. 2014 Mar;77(3):522-31. doi: 10.1111/bcp.12201. Related citations Select item 23812796 33 Risperidone, QTc interval prolongation, and torsade de pointes: a systematic review of case reports. Vieweg WV, Hasnain M, Hancox JC, Baranchuk A, Digby GC, Kogut C, Crouse EL, Koneru JN, Deshmukh A, Pandurangi AK. Psychopharmacology (Berl). 2013 Aug;228(4):515-24. doi: 10.1007/s00213-013-3192-8. Epub 2013 Jun 30. Review. Related citations Select item 23808912 34 QTc interval prolongation for patients in methadone maintenance treatment: a five years follow-up study. Fareed A, Vayalapalli S, Scheinberg K, Gale R, Casarella J, Drexler K. Am J Drug Alcohol Abuse. 2013 Jul;39(4):235-40. doi: 10.3109/00952990.2013.804525. Epub 2013 Jun 28. Related citations Select item 23791140 35 Escitalopram and QTc prolongation. Hasnain M, Howland RH, Vieweg WV. J Psychiatry Neurosci. 2013 Jul;38(4):E11. doi: 10.1503/jpn.130055. No abstract available. Free PMC Article Related citations Select item 23787716 36 QTc interval screening for cardiac risk in methadone treatment of opioid dependence. Pani PP, Trogu E, Maremmani I, Pacini M. Cochrane Database Syst Rev. 2013 Jun 20;6:CD008939. doi: 10.1002/14651858.CD008939.pub2. Review. Related citations Select item 23775057 37 High-dose oral ziprasidone versus conventional dosing in schizophrenia patients with residual symptoms: the ZEBRAS study. Goff DC, McEvoy JP, Citrome L, Mech AW, Bustillo JR, Gil R, Buckley P, Manschreck TC, Achtyes ED, Macklin EA. J Clin Psychopharmacol. 2013 Aug;33(4):485-90. doi: 10.1097/JCP.0b013e3182977308. Related citations Select item 23773986 38 Noninvasive cardiac activation imaging of ventricular arrhythmias during drug-induced QTprolongation in the rabbit heart. Han C, Pogwizd SM, Killingsworth CR, Zhou Z, He B. Heart Rhythm. 2013 Oct;10(10):1509-15. doi: 10.1016/j.hrthm.2013.06.010. Epub 2013 Jun 14. Related citations Select item 23771541 39 The effect of adrenaline on desflurane-induced prolonged QTc interval: a randomized double-blind trial. Bestas A, Hanbeyoglu O, Keles E, Bayar MK. Eur Rev Med Pharmacol Sci. 2013 Jun;17(11):1523-8. Free Article Related citations Select item 23745503 40 [QTc-prolongation in acute drug-poisoning. Guidelines for management from the Swedish Poisons Information Centre]. Höjer J. Lakartidningen. 2013 May 7-21;110(19-20):953-5. Swedish. No abstract available. Related citations
Drugs to Avoid
Drug-Induced QT Prolongation
Drug induced QT prolongation
Drug Induced QT Prolongation
Q-Tc Interval Prolongation by Drugs: Antiarrhythmic Drug Actions
Center for Education and Research Therapeutics
Publications
1 Methadone, QTc prolongation and torsades de pointes: Current concepts, management and a hidden twist in the tale? Mujtaba S, Romero J, Taub CC.J Cardiovasc Dis Res. 2013 Dec;4(4):229-235. Epub 2013 Nov 16. Review. PMID:24653586[PubMed - as supplied by publisher]Related citations Select item 24438862 2 Racial susceptibility for QT prolongation in acute drug overdoses. Manini AF, Stimmel B, Vlahov D.J Electrocardiol. 2014 Mar-Apr;47(2):244-50. doi: 10.1016/j.jelectrocard.2013.12.002. Epub 2013 Dec 4. PMID:24438862[PubMed - in process]Related citations Select item 24399590 3 Giant drug-induced QT prolongation > 800 ms with alternans of terminal portion of T wave and J wave in a normothermic patient. Kukla P, Baranchuk A, Jastrzębski M, Bryniarski L, Baranowski R.Kardiol Pol. 2013;71(12):1306-7. doi: 10.5603/KP.2013.0330. PMID:24399590[PubMed - indexed for MEDLINE] Free ArticleRelated citations Select item 24388488 4 Drug-induced QT prolongation when QT interval is measured in each of the 12 ECG leads in men and women in a thorough QT study. Panicker GK, Salvi V, Karnad DR, Chakraborty S, Manohar D, Lokhandwala Y, Kothari S.J Electrocardiol. 2014 Mar-Apr;47(2):155-7. doi: 10.1016/j.jelectrocard.2013.11.004. Epub 2013 Nov 27. PMID:24388488[PubMed - in process]Related citations Select item 24372552 5 Detection of QTc interval prolongation using jacket telemetry in conscious non-human primates: comparison with implanted telemetry. Derakhchan K, Chui RW, Stevens D, Gu W, Vargas HM.Br J Pharmacol. 2014 Jan;171(2):509-22. doi: 10.1111/bph.12484. PMID:24372552[PubMed - in process]Related citations Select item 24353019 6 Prolonged QT interval by methadone: relevance for daily practice? A prospective study in patients with cancer and noncancer pain. van den Beuken-van Everdingen MH, Geurts JW, Patijn J.J Opioid Manag. 2013 Jul-Aug;9(4):263-7. doi: 10.5055/jom.2013.0167. PMID:24353019[PubMed - indexed for MEDLINE]Related citations Select item 24327451 7 Evidence for a crucial modulating role of the sodium channel in the QTc prolongation related to antipsychotics. Silvestre JS, O'Neill MF, Prous JR.J Psychopharmacol. 2014 Apr;28(4):329-40. doi: 10.1177/0269881113515064. Epub 2013 Dec 10. PMID:24327451[PubMed - in process]Related citations Select item 24314265 8 Safety and efficacy of vemurafenib in end stage renal failure. Iddawela M, Crook S, George L, Lakkaraju A, Nanayakkara N, Hunt R, Adam WR.BMC Cancer. 2013 Dec 6;13:581. doi: 10.1186/1471-2407-13-581. PMID:24314265[PubMed - indexed for MEDLINE] Free ArticleRelated citations Select item 24313745 9 Adverse effects associated with high-dose olanzapine therapy in patients admitted to inpatient psychiatric care. Petersen AB, Andersen SE, Christensen M, Larsen HL.Clin Toxicol (Phila). 2014 Jan;52(1):39-43. doi: 10.3109/15563650.2013.862258. Epub 2013 Dec 9. PMID:24313745[PubMed - indexed for MEDLINE]Related citations Select item 24305646 10 Impact of anaesthetic drugs and adjuvants on ECG markers of torsadogenicity. Staikou C, Stamelos M, Stavroulakis E.Br J Anaesth. 2014 Feb;112(2):217-30. doi: 10.1093/bja/aet412. Epub 2013 Dec 3. Review. PMID:24305646[PubMed - indexed for MEDLINE]Related citations Select item 24301687 11 Assessment of drug-induced torsade de pointes risk for hospitalized high-risk patients receiving QT-prolonging agents. Jardin CG, Putney D, Michaud S.Ann Pharmacother. 2014 Feb;48(2):196-202. doi: 10.1177/1060028013512614. Epub 2013 Dec 3. PMID:24301687[PubMed - in process]Related citations Select item 24256556 12 Ibandronate and ventricular arrhythmia risk. Bonilla IM, Vargas-Pinto P, Nishijima Y, Pedraza-Toscano A, Ho HT, Long VP 3rd, Belevych AE, Glynn P, Houmsse M, Rhodes T, Weiss R, Hund TJ, Hamlin RL, Györke S, Carnes CA.J Cardiovasc Electrophysiol. 2014 Mar;25(3):299-306. doi: 10.1111/jce.12327. Epub 2013 Dec 20. PMID:24256556[PubMed - in process]Related citations Select item 24252288 13 QTc compared to JTc for monitoring drug-induced repolarization changes in the setting of ventricular pacing. Tsai SF, Houmsse M, Dakhil B, Augostini R, Hummel JD, Kalbfleisch SJ, Liu Z, Love C, Rhodes T, Tyler J, Weiss R, Hamam I, Winner M, Daoud EG.Heart Rhythm. 2014 Mar;11(3):485-91. doi: 10.1016/j.hrthm.2013.11.017. Epub 2013 Nov 16. PMID:24252288[PubMed - in process]Related citations Select item 24249315 14 Quetiapine versus other atypical antipsychotics for schizophrenia. Asmal L, Flegar SJ, Wang J, Rummel-Kluge C, Komossa K, Leucht S.Cochrane Database Syst Rev. 2013 Nov 18;11:CD006625. doi: 10.1002/14651858.CD006625.pub3. PMID:24249315[PubMed - in process]Related citations Select item 24211841 15 ECG parameters in children and adolescents treated with aripiprazole and risperidone. Germanò E, Italiano D, Lamberti M, Guerriero L, Privitera C, D'Amico G, Siracusano R, Ingrassia M, Spina E, Calabrò MP, Gagliano A.Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jun 3;51:23-7. doi: 10.1016/j.pnpbp.2013.10.020. Epub 2013 Nov 5. PMID:24211841[PubMed - in process]Related citations Select item 24211675 16 Effects of probucol, a typical hERG expression inhibitor, on in vivo QT interval prolongation in conscious dogs. Nogawa H, Kawai T, Yajima M, Miura M, Ogawa T, Murakami K.Eur J Pharmacol. 2013 Nov 15;720(1-3):29-37. doi: 10.1016/j.ejphar.2013.10.056. Epub 2013 Nov 5. PMID:24211675[PubMed - in process]Related citations Select item 24167694 17 Methadone, QTc interval prolongation and torsade de pointes: Case reports offer the best understanding of this problem. Vieweg WV, Hasnain M, Howland RH, Clausen T, Koneru JN, Kogut C, Crouse EL, Hancox JC, Fernandez A, Pandurangi AK.Ther Adv Psychopharmacol. 2013 Aug;3(4):219-32. doi: 10.1177/2045125312469982. PMID:24167694[PubMed] Free PMC ArticleRelated citations Select item 24135462 18 Serum concentration of eperisone hydrochloride correlates with QT interval. Yamagiwa T, Morita S, Amino M, Miura N, Saito T, Inokuchi S.Am J Emerg Med. 2014 Jan;32(1):75-7. doi: 10.1016/j.ajem.2013.09.006. Epub 2013 Oct 15. PMID:24135462[PubMed - indexed for MEDLINE]Related citations Select item 24131328 19 Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. Al-Abri SA, Orengo JP, Hayashi S, Thoren KL, Benowitz NL, Olson KR.Clin Toxicol (Phila). 2013 Dec;51(10):1230-4. doi: 10.3109/15563650.2013.849349. Epub 2013 Oct 17. PMID:24131328[PubMed - indexed for MEDLINE]Related citations Select item 24120715 20 High-quality triplicate electrocardiogram monitoring in a first-in-man study: potential for early detection of drug-induced QT prolongation. He YL, Zhang Y, Yan JH, Zhou W, Komjathy S, Taylor A.Int J Clin Pharmacol Ther. 2013 Dec;51(12):948-57. doi: 10.5414/CP201949. PMID:24120715[PubMed - indexed for MEDLINE]Related citations
21
Compound ICA-105574 prevents arrhythmias induced by cardiac delayed repolarization. Meng J, Shi C, Li L, Du Y, Xu Y. Eur J Pharmacol. 2013 Oct 15;718(1-3):87-97. doi: 10.1016/j.ejphar.2013.09.011. Epub 2013 Sep 13. Related citations Select item 24020938
22 QT interval prolongation and the risk of torsades de pointes: essentials for clinicians. Trinkley KE, Lee Page R 2nd, Lien H, Yamanouye K, Tisdale JE. Curr Med Res Opin. 2013 Dec;29(12):1719-26. doi: 10.1185/03007995.2013.840568. Epub 2013 Sep 23. Related citations Select item 23999693 23 Exposure-response analysis of pertuzumab in HER2-positive metastatic breast cancer: absence of effect on QTc prolongation and other ECG parameters. Garg A, Li J, Clark E, Knott A, Carrothers TJ, Marier JF, Cortés J, Brewster M, Visich J, Lum B. Cancer Chemother Pharmacol. 2013 Nov;72(5):1133-41. doi: 10.1007/s00280-013-2279-6. Epub 2013 Sep 3. Free PMC Article Related citations Select item 23995305 24 Slow delayed rectifier potassium current blockade contributes importantly to drug-induced long QT syndrome. Veerman CC, Verkerk AO, Blom MT, Klemens CA, Langendijk PN, van Ginneken AC, Wilders R, Tan HL. Circ Arrhythm Electrophysiol. 2013 Oct;6(5):1002-9. doi: 10.1161/CIRCEP.113.000239. Epub 2013 Aug 31. Related citations Select item 23920817 25 Early detection of QT interval prolongation from the ECG database system. Yamaguchi I, Fujita H, Ohe K. Stud Health Technol Inform. 2013;192:1043. Related citations Select item 23899678 26 Risk of QTc prolongation in a cohort of opioid-dependent HIV-infected patients on methadone maintenance therapy. Vallecillo G, Mojal S, Roquer A, Martinez D, Rossi P, Fonseca F, Muga R, Torrens M. Clin Infect Dis. 2013 Oct;57(8):1189-94. doi: 10.1093/cid/cit467. Epub 2013 Jul 29. Related citations Select item 23892340 27 Spatial correlation of action potential duration and diastolic dysfunction in transgenic and drug-induced LQT2 rabbits. Odening KE, Jung BA, Lang CN, Cabrera Lozoya R, Ziupa D, Menza M, Relan J, Franke G, Perez Feliz S, Koren G, Zehender M, Bode C, Brunner M, Sermesant M, Föll D. Heart Rhythm. 2013 Oct;10(10):1533-41. doi: 10.1016/j.hrthm.2013.07.038. Epub 2013 Jul 26. Related citations Select item 23869656 28 A case series of patients with lamotrigine toxicity at one center from 2003 to 2012. Moore PW, Donovan JW, Burkhart KK, Haggerty D. Clin Toxicol (Phila). 2013 Aug;51(7):545-9. doi: 10.3109/15563650.2013.818685. Epub 2013 Jul 19. Related citations Select item 23842012 29 Termination of clozapine treatment due to medical reasons: when is it warranted and how can it be avoided? Nielsen J, Correll CU, Manu P, Kane JM. J Clin Psychiatry. 2013 Jun;74(6):603-13; quiz 613. doi: 10.4088/JCP.12r08064. Review. Related citations Select item 23833046 30 Epidemiology of symptomatic drug-induced long QT syndrome and Torsade de Pointes in Germany. Sarganas G, Garbe E, Klimpel A, Hering RC, Bronder E, Haverkamp W. Europace. 2014 Jan;16(1):101-8. doi: 10.1093/europace/eut214. Epub 2013 Jul 5. Related citations Select item 23820570 31 QTc interval screening in an opioid treatment program. Katz DF, Sun J, Khatri V, Kao D, Bucher-Bartelson B, Traut C, Lundin-Martinez J, Goodman M, Mehler PS, Krantz MJ. Am J Cardiol. 2013 Oct 1;112(7):1013-8. doi: 10.1016/j.amjcard.2013.05.037. Epub 2013 Jun 29. PMID: 23820570 [PubMed - indexed for MEDLINE] Related citations Select item 23819796 32 Are women more susceptible than men to drug-induced QT prolongation? Concentration-QTcmodelling in a phase 1 study with oral rac-sotalol. Darpo B, Karnad DR, Badilini F, Florian J, Garnett CE, Kothari S, Panicker GK, Sarapa N. Br J Clin Pharmacol. 2014 Mar;77(3):522-31. doi: 10.1111/bcp.12201. Related citations Select item 23812796 33 Risperidone, QTc interval prolongation, and torsade de pointes: a systematic review of case reports. Vieweg WV, Hasnain M, Hancox JC, Baranchuk A, Digby GC, Kogut C, Crouse EL, Koneru JN, Deshmukh A, Pandurangi AK. Psychopharmacology (Berl). 2013 Aug;228(4):515-24. doi: 10.1007/s00213-013-3192-8. Epub 2013 Jun 30. Review. Related citations Select item 23808912 34 QTc interval prolongation for patients in methadone maintenance treatment: a five years follow-up study. Fareed A, Vayalapalli S, Scheinberg K, Gale R, Casarella J, Drexler K. Am J Drug Alcohol Abuse. 2013 Jul;39(4):235-40. doi: 10.3109/00952990.2013.804525. Epub 2013 Jun 28. Related citations Select item 23791140 35 Escitalopram and QTc prolongation. Hasnain M, Howland RH, Vieweg WV. J Psychiatry Neurosci. 2013 Jul;38(4):E11. doi: 10.1503/jpn.130055. No abstract available. Free PMC Article Related citations Select item 23787716 36 QTc interval screening for cardiac risk in methadone treatment of opioid dependence. Pani PP, Trogu E, Maremmani I, Pacini M. Cochrane Database Syst Rev. 2013 Jun 20;6:CD008939. doi: 10.1002/14651858.CD008939.pub2. Review. Related citations Select item 23775057 37 High-dose oral ziprasidone versus conventional dosing in schizophrenia patients with residual symptoms: the ZEBRAS study. 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