Guidelines for Chemotherapy & Hazardous Drugs
DailyMed Advanced Search Medicines Micromedex UpToDate
ASHP Guidelines on Handling Hazardous Drugs - America
CDC - Hazardous Drug Exposures in Health Care
Chemotherapy Administration in Non-Oncology Settings
Prevention Guide - Safe Handling of Hazardous Drugs
Safe Handling of Hazardous Drugs
Safe Handling of Hazardous Drugs - BC Cancer Agency
Safety and Health Topics | Hazardous Drugs - OSHA
Administration of Chemotherapeutic Agents in Non-Oncology Setting
Chemotherapy drugs are increasingly being administered for non-oncology purposes and in non-oncology areas. This practice shift raises valid concerns about nursing training, safe handling practices, side effect and oncologic emergency management, and, ultimately, patient and nurse safety. - See more at: Chemotherapy Administration in Non-Oncology Settings
DailyMed Advanced Search Medicines Micromedex UpToDate
ASHP Guidelines on Handling Hazardous Drugs - America
CDC - Hazardous Drug Exposures in Health Care
Chemotherapy Administration in Non-Oncology Settings
Prevention Guide - Safe Handling of Hazardous Drugs
Safe Handling of Hazardous Drugs
Safe Handling of Hazardous Drugs - BC Cancer Agency
Safety and Health Topics | Hazardous Drugs - OSHA
Administration of Chemotherapeutic Agents in Non-Oncology Setting
Chemotherapy drugs are increasingly being administered for non-oncology purposes and in non-oncology areas. This practice shift raises valid concerns about nursing training, safe handling practices, side effect and oncologic emergency management, and, ultimately, patient and nurse safety. - See more at: Chemotherapy Administration in Non-Oncology Settings
Frequently Used Drugs
Anastrozole (Arimidex®) (PO) Azathioprine (Imuran®) (PO) Bicalutamide (Casodex®) (PO) Capecitabine (Xeloda®) (PO) Chlorambucil (Leukeran®) (PO) Dutasteride (Avodart®) (PO) Erlotinib (Tarceva®) (PO) Finasteride (Proscar®) (PO) Flutamide (Eulexin®) (PO) Fulvestrant (Faslodex®) (PO) Ganciclovir (Cytovene®) (IV) Goserelin Acetate (Zoladex®) (PO) Hydroxyurea (Hydrea®) (PO) Imatinib Mesylate (Gleevec®) (PO) Lapatinib (Tykerb®) (PO) Letrozole (Femara®) (PO) Leuprolide Acetate (Lupron®) (PO) Megestrol Acetate (Megace®) (PO) Melphalan (Alkeran®) (PO) Mercaptopurine (Purinethol®) (PO) Mitotane (Lysodren®) (PO) Sorafenib (Nexavar®) (PO) Sunitinib (Sutent®) (PO) Tamoxifen (Nolvadex®) (PO) Temozolomide (Temadar®) (PO) Topotecan (Hycamtin®) (PO) Hazardous Drug List – High-Risk Medications Drug Dosage Form - Classification Ado-trastuzumab Injection - Antineoplastic Aldesleukin Injection - Antineoplastic Alemtuzumab Injection - Antineoplastic Arsenic trioxide Injection - Antineoplastic Asparaginase Injection - Antineoplastic Azacitidine Injection - Antineoplastic Bendamustine Injection - Antineoplastic Bevacizumab Injection - Antineoplastic Bleomycin Injection - Antineoplastic Bortezomib Injection - Antineoplastic Brentuximab Injection - Antineoplastic Busulfan Injection - Antineoplastic Cabazitaxel Injection - Antineoplastic Carboplatin Injection - Antineoplastic Carfilzomib Injection - Antineoplastic Carmustine Injection - Antineoplastic Cetuximab Injection - Antineoplastic Cidofovir Injection - Antiviral Cisplatin Injection - Antineoplastic Cladribine Injection - Antineoplastic Clofarabine Injection - Antineoplastic Cyclophosphamide Injection - Antineoplastic Cytarabine (including liposomal) Injection - Antineoplastic Dacarbazine Injection - Antineoplastic Dactinomycin Injection - Antineoplastic Daunorubicin (including liposomal) Injection - Antineoplastic Decitabine Injection - Antineoplastic Degarelix Injection - Antineoplastic Dexrazoxane Injection - Cardioprotectant Denileukin Injection - Antineoplastic Docetaxel Injection Antineoplastic Doxorubicin (including liposomal) Injection - Antineoplastic Epirubicin Injection - Antineoplastic Eribulin Injection - Antineoplastic Etoposide Injection - Antineoplastic Floxuridine Injection - Antineoplastic Fludarabine Injection - Antineoplastic Fluorouracil Injection - Antineoplastic Gemcitabine Injection - Antineoplastic Idarubicin Injection - Antineoplastic Ifosfamide Injection - Antineoplastic Ipilimumab Injection - Antineoplastic Irinotecan Injection - Antineoplastic Ixabepilone Injection - Antineoplastic Mechlorethamine Injection - Antineoplastic Melphalan Injection - Antineoplastic Methotrexate Injection - Antineoplastic Mitomycin Injection - Antineoplastic Mitoxantrone Injection - Antineoplastic Nelarabine Injection - Antineoplastic Ofatumumab Injection - Antineoplastic Oxaliplatin Injection - Antineoplastic Paclitaxel Injection - Antineoplastic Panitumumab Injection - Antineoplastic Pegaspargase Injection - Antineoplastic Pemetrexed Injection - Antineoplastic Pentetate calcium trisodium Injection - Chelating Agent Pentostatin Injection - Antineoplastic Pertuzumab Injection - Antineoplastic Pralatrexate Injection - Antineoplastic Ribavirin Inhalation - Antiviral Rituximab Injection - Antineoplastic Romidepsin Injection - Antineoplastic Streptozocin Injection - Antineoplastic Temozolomide Injection - Antineoplastic Temsirolimus Injection - Antineoplastic Teniposide Injection - Antineoplastic Thiotepa Injection /Intravesical - Antineoplastic Topotecan Injection - Antineoplastic Trastuzumab Injection - Antineoplastic Valrubicin Intravesical - Antineoplastic Vinblastine sulfate Injection - Antineoplastic Vincristine liposomal Injection - Antineoplastic Vincristine sulfate Injection - Antineoplastic Vinorelbine tartrate Injection - Antineoplastic Ziv-aflibercept Injection - Antineoplastic Hazardous Drugs – Reproductive Risk Medications Drug Dosage Form - Classification Bxarotene Oral and Topical - Retinoid Bicalutamide Oral - Antiandrogen Bosentan Oral - Vasodilating agent Cabergoline Oral - Ergot-derivative dopamine receptor agonist Carbamazepine Oral - Anticonvulsant Cetrorelix acetate Injection - GnRH antagonist Chorionic gonadotropin Injection - Gonadotropin Clomiphene citrate Oral - Estrogen receptor modifier Clonazepam Oral - Benzodiazepine Colchicine Oral - Antigout agent Dinoprostone (insert/gel) Topical - Prostaglandin Dronedarone Oral - Antiarrythmic Dutasteride (capsule) Oral - Antiandrogen Entecavir Oral - Nucleosides and nucleotides Ergonovine/methylergonovine Oral and Injection -Oxytocic Estradiol (tablet, topical) Oral and Topical - Hormone Estrogens (conjugated,esterified, estrone, estropipate, combined with progestin) - Oral and Topical Hormone Exemestane Oral - Aromatase inhibitor Finasteride (tablet) Oral - Antiandrogen Fluoxymesterone Oral - Antiandrogen Flutamide Oral - Antiandrogen Follitropin alfa, beta Injection - Follicle stimulating hormone Fulvestrant Injection - Estrogen receptor modifier Ganirelix acetate Injection - GnRH antagonist |
Approved Indication
Breast cancer for prevention or long-term maintenance Arthritis Advanced prostate cancer for long-term maintenance Breast and colorectal cancer for long-term maintenance CLL and Hodgkins maintenance Benign Prostatic Hypertrophy (BPH) Lung cancer maintenance BPH, prevention of progression of Stage I prostate cancer, prevention of male pattern baldness Prostate cancer for long-term maintenance Prostate and breast cancer for long-term maintenance Cytomegalovirus (CMV) infections Prostate and breast cancer for long-term maintenance Maintenance in melanoma, CML, ovarian, and head/neck cancer Maintenance in Myleodysplastic Syndrome, ALL, and CML Breast cancer for maintenance Breast cancer for prevention or long-term maintenance Prostate cancer for long-term maintenance Appetite stimulant in HIV and cancer patients Palliation Multiple myeloma for long-term maintenance In ALL for long-term maintenance Inoperable adrenal carcinoma Renal cancer for long-term maintenance GI stromal tumors for long-term maintenance Breast cancer for prevention or long-term maintenance Astrocytoma and glioblastoma long-term maintenance Lung cancer for maintenance Hazardous Drug List – Low-Risk Medications Drug Dosage Form - Classification Altretamine Oral - Antineoplastic Alefacept Injection - Immunosuppressant Anti-thymocyte globulin Injection - Immunosuppressant Axitinib Oral - Antineoplastic Azathioprine (injection and tablet) - Immunosuppressant Bosutinib Oral - Antineoplastic Busulfan Oral - Antineoplastic Cabozantinib Oral - Antineoplastic Capecitabine Oral - Antineoplastic Chlorambucil Oral - Antineoplastic Chloramphenicol Injection - Antibiotic Crizotinib Oral - Antineoplastic Cyclophosphamide Oral - Antineoplastic Cyclosporine Injection, Oral and Ophthalmic - Immunosuppressant Dasatinib Oral - Antineoplastic Erlotinib Oral - Antineoplastic Estrasmustine Oral - Antineoplastic Etoposide Oral - Antineoplastic Everolimus Oral - Antineoplastic Fludarabine Oral - Antineoplastic Fluorouracil Topical - Antineoplastic Ganciclovir Oral, Injection and Ophthalmic - Antiviral Hydroxyurea Oral - Antineoplastic Imatinib mesylate Oral - Antineoplastic Lapatinib Oral - Antineoplastic Lomustine Oral - Antineoplastic Melphalan Oral - Antineoplastic Mercaptopurine Oral - Antineoplastic Methotrexate Oral and Topical - Antineoplastic Mitotane Oral - Antineoplastic Mycophenolate Oral and Injection - Immunosuppressant Nilotinib Oral - Antineoplastic Pazopanib Oral - Antineoplastic Pentamidine isethionate Injection/Inhalation -Antiprotozoal Phenoxybenzamine Oral - Non-selective alphaadrenergic blocking agent Plerixafor Injection - Hematopoietic agent Podofilox Topical - Mitotic inhibitor Ponatinib Oral - Antineoplastic Porfimer Injection - Antineoplastic Procarbazine Oral - Antineoplastic Ribavirin Oral - Antiviral Regorafenib Oral - Antineoplastic Sirolimus Oral - Immunosuppressant Sorafenib Oral - Antineoplastic Sunitinib Oral - Antineoplastic Tacrolimus Oral, Injection and Topical Immunosuppressant Temozolomide Oral - Antineoplastic Thioguanine Oral - Antineoplastic Topotecan Oral - Antineoplastic Trifluridine Ophthalmic - Antiviral Valganciclovir Oral - Antiviral Vandetanib Oral - Antineoplastic Vemurafenib Oral - Antineoplastic Verteporfin Injection - Photoenhancer Vismodegib Oral - Antineoplastic Vorinostat Oral - Antineoplastic Zidovudine Oral and Injection - Antiretroviral agent Hazardous Drugs – Reproductive Risk Medications Drug Dosage Form - Classification Goserelin Injection - GnRH agonist Histrelin acetate Injection - GnRH agonist Isotretinoin Oral - Retinoid Leflunomide Oral - Biologic response modifier Lenalidomide Oral - Biologic response modifier Letrozole Oral - Aromatase inhibitor Leuprolide acetate Injection - GnRH agonist Medroxyprogesterone acetate Oral and Injection -Hormone Megestrol acetate Oral - Gonadotropin Injection Injection - Gonadotropin Methyltestosterone Oral Androgen Mifepristone Oral - Oxytocic Misoprostol Oral - Oxytocic Nafarelin Topical - GnRH agonist Nilutamide Oral - Antiandrogen Oxytocin Injection - Oxytocic Oxandrolone Oral - Androgen Oxcarbazepine Oral - Anticonvulsant Oxymetholone Oral - Androgen Palifermin Injection - Keratinocyte growth factor Paroxetine Oral - Antidepressant Podophyllum resin Topical - Mitotic inhibitor. Progesterone (tablet, injection,gel) - oral /Injection/Topical Hormone Progestins Oral - Hormone Raloxifene Oral - Estrogen receptor modifier Rasagiline mesylate Oral - Antiparkinsonian agent Risperidone Oral and Injection - Atypical antipsychotic Tamoxifen Oral - Estrogen receptor modifier Tazarotene -Topical Retinoid Telavancin Injection- Glycopeptide Testosterone Oral and Topical Androgen Tetracycline HCl Oral Antibiotic Thalidomide Oral Biologic response modifier Toremifene citrate Oral Estrogen receptor modifier Tretinoin (capsule, cream, gel) Topical Retinoid Triptorelin Injection GnRH agonist Valproic acid/divalproex Na Oral and Injection Anticonvulsant Vigabatrin Oral - Anticonvulsant Ziprasidone Oral and Injection - Atypical antipsychotic Zolendronic Acid Injection - Bone resorption inhibitor |