Hospital Pharmacists Information System
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Stages and timeline

Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patient. For orally taken drugs, this usually involves incorporating the drug into a tablet or a capsule. It is important to appreciate that a tablet contains a variety of other substances apart from the drug itself, and studies have to be carried out to ensure that the drug is compatible with these other substances.

Preformulation involves the characterization of a drug's physical, chemical, and mechanical properties in order to choose what other ingredients (known as excipients) should be used in the preparation. In dealing with protein pre-formulation, the important aspect is to understand the solution behavior of a given protein under a variety of stress conditions such as freeze/thaw, temperature, shear stress among others to identify mechanisms of degradation and therefore its mitigation.

  • Stages and timeline
  • 2 Formulation Types
  • 3 Enteral Formulations
    • 3.1 Tablet
    • 3.2 Capsule
    • 3.3 Sustained Release
  • 4 Parenteral Formulations
    • 4.1 Liquid
    • 4.2 Lyophilized
  • 5 Topical Formulations
    • 5.1 Cutaneous
    • 5.2 Inhaled
  • 6 See also
  • 7 References

Drug Stability Related Websites

Acceptable duration at room temperature for medications 

Controlled Room Temperature - USP 797 - Questions and

Creation of a Temperature Stability Database

Drug Stabilty

Drug stability chart nr D0106 Ed01 - B. Braun Medical B.V.

Drug Information Resource Guide

Guidance for Industry #5 - Drug Stability Guidelines Room-temperature Storage of Medications Labeled

Drug stability chart nr D0106 Ed01 - B. Braun Medical B.V.

Room-temperature storage of medications labeled for

Room-temperature storage of medications labeled for

Room-temperature storage of medications labeled for refrigeration

Stability testing - World Health Organization

Stability of Refrigerator and Frozen Drugs

What is the General definition for drug stability and the factors